Medical magazine He withdrew two studies While a federal judge in Texas decides that the drug should be removed from the market, the abortion pill is to examine the security of Mifepriston.
Both of them claim that abortions containing mifepristone are associated with a serious risk of complications compared to procedural abortions. Contrary to these results hundreds of work Mifepriston, who has been approved by the US Food and Pharmaceutical Administration for 10 weeks of pregnancy in abortion by the US Food and Pharmaceutical Administration, was safe and effective. Mifepriston The drug is used in combination with misoprostol Almost all drug abortions in the US and drug abortions in 2020 have formed more than half of the country -wide abortions.
A third study, written by the same authors but refused by the judge, withdrew; Mifepriston was about doctors who prescribed it. All three articles have been published Health Services Research and Management Epidemiology, Published by Sage Journals. They appeared in the magazine in 2019, 2021 and 2022.
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The articles drew attention after the Hippocratic Medicine Alliance with a group of antiabortion doctor and organization. USA filed a lawsuit against Food and Pharmaceuticals The alliance did not follow the appropriate procedures to confirm the FDA’s medicine more than twenty years ago. He underestimated Mifepriston’s risks. The alliance while opening the case Pre -precautionary measures requested To remove Mifepriston from the market immediately.
In the court documents, the US Department of Justice (representing FDA on legal issues) described this request as “extraordinary and unprecedented”. . Doj discussed “The plaintiffs did not point to any case, and the government could not find any example of a court that FDA predicted the security and activity determination of the FDA and ordered it to be removed from the market.
Last April, when Judge Matthew Kacsmark from the Northern Region of Texas decided that the alliance continued to sue, the plaintiffs said that Mifepristone has brought a heavy burden to the emergency physicians who treat pregnant people with medical complications. KACSMARYK made a preliminary decision that invalidates the FDA’s Mifepriston approval.
The Supreme Court stopped the decision until the US fifth circuit appeal court decided. That court Hit some of Kacsmaryk A few days later, he decided, allowing Mifepristone to remain on the market with certain restrictions.
The decision of the Court of Appeal is evaluated by the Supreme Court, which is planned to be discussed in this March.
Now, Mifepristone remains During 10 weeks of pregnancy, with recipes permitted by telet and mail in states where abortion is legal.
Safety of Mifepristo
Research, MİFEPRISTONE used by more than five million pregnant people in the USA Approved in 2000San Francisco says Professor and Public Health Scientist Ushma Upadhyay at the University of California. “Judge KACSMARYK’s decision ignored science, and relying on a few cherries who chose a few cherries that supported their beliefs about abortion, Up said Upadhyay, the author of a new study. Posted last week Nature Medical– He found that the Mifepriston could be prescribed safely by concealing and considering it.
A coalition of medical groups – American women’s innkeeper and gynecologists And American Medical Association– Define the evidence of Mifepriston’s security as “overwhelming ..
Less than 1 percent of drug users have serious side effects, occurring, According to a short time Before the decision of the KACSMARYK of the medical groups, he applied to the US Regional Court for the Texas region of the USA. Large adverse events such as significant infection, blood loss or hospitalization are less than 0.3 percent.
Deaths are even rare. According to FDA, 24 million women who used Mifepristone to end pregnancy in the US between 2000-2018 died. This number recently includes those who deceased for a reason not attributed to it, such as murder, suicide or overdose of murder, suicide or overdose. HE Equal to mortality rate 0.00065 percent.
“There is almost no risk of death, or he says. “Mifepristone is one of the most examined drugs prescribed in the United States and has a comparable security profile. [that of] ibuprofen. “
A study published in the journal Contraception I found this last year The risk of death from pregnancy and birth It is at least 35 times higher than legal abortion.
Controversial studies
In a statement on the website, Sage Journals said that. two independent experts asked After expressing a reader’s concerns about the methodology of the articles and authors’ concerns about unprofessional conflicts of interest, to review Mifepristone.
In the 2021 study, which examined patient data between 1999-2015, researchers found that the visits of the Emergency Department related to abortion were more likely to be more likely than procedural abortion after abortion using Mipriston. This concluded that “Mifepriston abortion is continuously and increasing morbidity ,, compared to procedural abortions.
However, the study, which focuses on people covered by Medicaid, offers little evidence that these individuals have experienced a negative event about abortion.
In the 2021 study, pregnant people could go to the emergency room for any reason from food poisoning to the ears, Adkins added that he did not speak for the university. Research, half of the emergency service visits after abortion It has nothing to do with abortion. And many people, including those who are often entitled to Medicaid, go to the emergency department with non -emergency needs because they cannot access maintenance anywhere else.
Adkins, some people with medicine abortion visit emergency departments. “To determine whether the amount of bleeding and cramps is normal, Ad Adkins says. “A significant part of these visits is not a real negative event about abortion, but only observational care.”
Adkins says that the 2021 study could not provide significant context, including a significant increase in Medicaid recording during the working period (between 1999-2015), as a result of the appropriate Maintenance Law. Number of Americans Registered to Medicaid In 2000, it rose from 34.1 million to 71.5 million in 2015.
Although the authors of the 2021 article have announced that there was no conflict of interest when they sent it to publish, they were all attached to the Charlotte Lozier Institute, Elliot Institute, and anti-anti-exchanging groups, including pro-life obstal experts and gynecologists. Susan B. Anthony Pro-Life America, an effective anti-antiabortion group, has been financed by Charlotte Lozier Institute of the Institute of Research and Education, an effective anti-antiabortion group.
A peer commentator who initially evaluated the articles was attached to the Charlotte Lozier Institute at the time, and the publisher later concluded that the study of the study was “unreliable”.
Independent experts who propose three retreats found that the articles between 2021 and 2022 contained the misleading presentations of data showing a lack of scientific equipment lack of scientific equipment in the analysis and views of the authors’ basic problems, unjust or false factual assumptions, data.
James Studnicki is the chief author of all three studies and Vice President and Director of Data Analysis at the Charlotte Lozier Institute, POINT-BY POIN PUBLISHED REBUTTAL Criticism of Sage magazines. He and his joint writers did not attempt to hide their relationship. The articles contained a short biography that draws attention to the relations of researchers. In a response with e-mail Scientific American, A SAGE magazine spokesperson: “In the studies sent, individual decisions are based on magazine editors. These magazine editors rely on peer commentators to make a corrective action when necessary to evaluate the quality of a sent article and to determine whether it is acceptable to be published.”
Studnicki and Tessa Longbons, a senior research assistant at the Charlotte Lozier Institute and a joint writer of three articles, claim that their work is aimed at politics. In a video Sent onlineStudnicki claimed that most medical magazines were “Proabortion with resistance ..
“This event points to a larger, more new phenomenon, that is, many of our scientific institutions and publications are no longer advocated, S Scientific American. “We see an elite faction with prejudiced factions in the medical community with all the power that tries to suppress any research against pro -abortion narratives.
The critics of the back articles say that their concerns are practical – not personal or political.
“This is not about ideology, Up Upadhyay says. “The withdrawal of these studies is based on the defective scientific approaches that greatly disrupt the degree of safety for abortion.”
Its impact on future legal decisions
The Faculty of Law, who examines the history of abortion, Davis, Mary Ziegler, a professor at the University of California, says, “There is no legal possibility of making a lot of differences in the future court decisions or withdrawal.
Ziegler says that deputies who try to restrict abortion or restrict or restrict illegal abortion are more motivated than the concerns of protection from potential negative events with the desire to protect the fetus.
The Fifth Circuit Court of Appeal says that the decision of the Mifepristone is based on other testimonies, not back articles.
Supreme Court that voted to overthrow in 2022 Roe / Wade (In 1973, the turning point that legalized abortion is low by the retractions, Ziegler says Ziegler. “Considering the problems related to the standing case of the plaintiffs, the court may already be connected to the Hippocratic Medicine Alliance,” he says. He doesn’t do more than strengthening the position. “
