Pig Lived was successfully transmitted to people for the first time at the Chinese Military Hospital
They can lead to the use of pig liver to keep people alive by Chinese scientists, while waiting for a suitable human donor who can last for months or even years
For the first time, a pig liver was successfully transmitted to a person. Scientists say that the pig can be used to keep people alive at the end of their liver, and that they can be used when waiting for a suitable human donor who can last for months or even years.
Chinese scientists have genetically changed a miniature pig to minimize the risk of organ rejection before transporting his liver to a dead human patient. Bile successfully produced and maintained stable blood flow, and researchers say that pig liver can now “solve severe liver failure problem”.
Professor Lin Wang, a working writer from the fourth military medical university in the state of Xi’an, said, “The liver collected from the modified pig served very well in the human body. This surgery was really successful. The flow is very smooth. Very smooth. We function very well.
There are more than 600 people with liver disease in the UK, which is currently in need of transplantation. Life -saving surgery is also performed for some patients with primary liver cancer and children with metabolic diseases.
The breakthrough findings of the Nature Journal argue that genetically modified pig liver can survive and function in the human body. Scientists also followed the liver’s ability to perform nuclear functions, blood flow and immune and inflammatory responses for a 10 -day period.
The demand for the liver donor liver exceeds the supply very much, so that the organs of the pigs are considered as a possible alternative for a long time, considering the similarity of people’s people. Previously, scientists have been able to transport people with pork kidneys and hearts, but these organs mostly have a function.
A liver transplant proved to be difficult for more than a decade, because Professor Wang said it was “a big obstacle for us to overcome it”. These functions include blood filtering, metabolizing nutrients, detoxifying harmful substances, producing bile for digestion and storage of basic nutrients. In 2013, scientists made liver transplantation from the first pig.
Rafael Matesanz, the founder of the National Transplantation Organization in Spain, said, “This is the first transplant of a genetically modified pig liver to a dead person. The ultimate purpose of the experiment was to serve as a ‘bridge organ’ for acute liver failure, but to serve as a human organ for the acute liver organ.
Mr. Mateesanz added that similar transplants can be carried in “near the future” in living organisms.
The experiment was terminated after 10 days due to the demands made by the family of the dead patient. Scientists need more research on long -term results.
The liver had six genes to increase compatibility when he was transferred to human beings. “Pig liver can survive with the original liver of man and perhaps give additional support to him.”
Professor Wang said that his team wanted to transport pig liver to people who are not dead in the future, but in China, there are “many rules” around it.
Only basic liver functions were evaluated and could not collect longer -term data on more complex liver functions such as the team, drug metabolism, detoxification or immune function.
Professor Iván Fernández Vega, an expert at the University of Oviedo in Spain, said, iz We need to be careful. The study represents a milestone on the history of liver xenotransplantation. Sophisticated genetic modifications can be reorganized one of the most critical accommodation.
